BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide — a chain of 15 amino acids — derived from a naturally occurring protective protein found in gastric juice. It has become one of the most extensively studied peptides in preclinical research, with over 100 published studies examining its potential mechanisms of action.
What Is BPC-157?
BPC-157 is a partial sequence of a larger protein known as Body Protection Compound, which is naturally present in human gastric fluid. The synthetic version used in research settings is a stable, water-soluble peptide that has demonstrated remarkable stability across a range of pH levels, which is unusual for peptides of this size.
Researchers working with BPC-157 typically source it as a lyophilised (freeze-dried) powder that requires reconstitution with bacteriostatic water before use in experimental protocols.
Key Areas of Research
The existing body of preclinical literature on BPC-157 spans several key areas:
- Tissue repair mechanisms — Multiple animal model studies have investigated BPC-157's role in connective tissue, muscle, and tendon repair pathways, with results suggesting it may upregulate growth factor expression including VEGF and FGF.
- Gastrointestinal research — Given its gastric origin, significant research has focused on BPC-157's potential protective effects on gastrointestinal mucosal integrity in animal models.
- Nitric oxide system interaction — Research suggests BPC-157 may modulate the nitric oxide (NO) system, which plays a fundamental role in vascular function, inflammation, and cellular signalling.
- Neuroprotective properties — Emerging preclinical data has examined BPC-157's potential interactions with dopaminergic and serotonergic systems.
BPC-157 and TB-500: A Common Research Combination
Researchers frequently study BPC-157 alongside TB-500 (Thymosin Beta-4), another peptide involved in tissue repair pathways. While BPC-157 research focuses on localised repair mechanisms and growth factor upregulation, TB-500 research centres on cell migration and anti-inflammatory pathways. The BPC-157 / TB-500 combination is one of the most popular research configurations in the peptide field.
Reconstitution and Storage
BPC-157 should be reconstituted with bacteriostatic water and stored at 2–8°C once in solution. Our peptide dosage calculator can help researchers determine the correct reconstitution volumes for their experimental protocols.
For detailed reconstitution instructions, see our complete reconstitution guide.
Quality Assurance
All BPC-157 available through Regen Peptides is independently tested for purity (≥99%) with full Certificates of Analysis available for every batch. Third-party HPLC and mass spectrometry verification ensures researchers can trust the integrity of their experimental compounds.
This article is for educational and informational purposes only. All peptides sold by Regen Peptides are strictly for in-vitro research and laboratory use. Not for human consumption.
